MIPs

Molecularly Imprinted Polymers for selective extraction of analytes from complex matrices

AFFINIMIP® SPE are high performance Solid Phase Extraction sorbents based on molecularly imprinted polymers (MIP) for sample cleanup before chromatographic analytical methods. Thanks to the superior selectivity in comparison with standard SPE, analytical chemists obtain higher recovery yields using simple and ready-to-use protocol.  

Features & Benefits

• Perfect sample cleanup and lower detection limits.
• Stable at broad pH ranges and high temperatures.
• Reduction of ion suppression.

Ion suppression is a problematic phenomenon that occurs when analyzing trace levels of analyte(s) in complex matrices with hyphenated techniques such as LC-MS-MS (Liquid Chromatography - tandem Mass Spectrometry). It is caused by the co-elution of matrix components with analyte(s) of interest and negatively affects several analytical figures of merit such as detection capability, precision and accuracy. Therefore, a perfect sample cleanup during sample preparation is critical. Thanks to the selectivity of AFFINIMIP® technology, ion suppression is reduced compared to more conventional SPE phases.